House M.D. is a different kind of medical drama that is centered around Dr. Gregory House, a somewhat bitter, mildly antisocial, Vicodin addicted yet brilliant doctor who, along with a small staff, seeks out cures to mysterious and often devastating medical illnesses. The show takes place at a teaching hospital in New Jersey. Since most of the patients who are to be treated by House and his team are undiagnosed or misdiagnosed, the show hinges on the group of doctors utilizing everything they have to try to deduce the cure. House's team is comprised of doctors Eric Foreman, Allison Cameron, Chris Taub, Lawrence Kutner, and a woman known simply as "Thirteen". House's unconventional sometimes unethical actions often land him in trouble with Dr. Lisa Cuddy, the Dean of Medicine and hospital administrator.

The team treats a woman with an exhaustive work schedule and a demanding boss, but House is too preoccupied with Wilson to provide much help.

Several patients who all received organs from the same donor have died and the sole remaining patient is brought to House and the team, making them race against the clock to try to save her.

What did House find when he investigated his staff? Did Dr. Cuddy have a date?

A woman searches for her birth parents in China and House's dad dies.

Thirteen's personal life spills over into her professional life and she ends up getting fired.

House and his team try to diagnose a single father who is suffering from blackouts and memory loss and Cuddy finds a mother having a baby for her to adopt.

House and Cuddy try to deal with the aftermath of their kiss while the team tries to help a severely ill man who's agoraphobia keeps him from entering the hospital.

An emancipated teen is brought to House and his team with a mysterious heart problem that caused her to collapse at work, meanwhile, Foreman finds a way to take on more work.

A sick man takes House, 13 and other patients hostage and demands to be diagnosed.

An all-natural fitness instructor suddenly becomes ill and is brought to House and Kutner tries to keep a secret.

House, Cuddy and the team try to figure out what is making a teenage girl sick. House also proves he can be nice by working in the clinic.

House and the team treat a suicidal man who has intestinal pains while Foreman gives Thirteen hope.

Cameron takes over Cuddy's job while the team attempt to diagnose a sick special needs teacher.

House discovers that payback is a pain while Foreman tells Thirteen the truth about her clinical trial.

House takes interest in the case of a priest who hallucinated Jesus.

A child with both genders collapses and the team notices something is different about House.

A man's mysterious illness causes him to act like House.

House has help from a feline in the diagnosis of a patient that the rest of the team think is faking.

House works on a patient who can only communicate by blinking. Guest starring Mos Def as Lee.

Taub treats a woman who is getting sicker as her dying husband gets better. Meanwhile, the doctors must cope with the shocking loss of one of the team.

Cameron blows off Chase to work with House and everyone tries to figure out her motives.

Amber appears to House they try to diagnose a deaf boy who became ill during a wrestling match.

House struggles to rid himself of his visions of Amber and he turns to someone unexpected for help. Meanwhile, the team tries to save a ballerina without help from House.

The team treats a man whose brain has split in two, Cameron and Chase have reached a decision about their relationship, and House toys with Cuddy over his detox.

House tries to check out of a mental hospital, but learns that he will not be able to practice medicine if he doesn't show signs of improvement. Later, House learns that deductive reasoning is not the only way to learn about people.

House quits the hospital and picks up cooking in order to get his mind of his pain. Foreman takes over his job, but finds his staff deserting him.

House returns to the staff as a consultant to diagnose a brutal dictator who coughs up blood in this episode with guest star James Earl Jones.

A rich billionaire thinks his son is sick because of his good financial fortune. Meanwhile, Chase and Foreman debate on how they should cover up the Dibala's murder.

The team treats a man whose father died from an heart attack when they reached the age of 40. House hears voices while he sleeps in Amber's old room while Chase feels guilty for murdering Dibala.

The team attends a medical conference where House plans on seducing Cutty and sabotaging Wilson's presentation. Meanwhile back home, the doctors treat a girl who has a problem of telling the truth.

House uses a case about a sick pornstar to recruit his old team back. Meanwhile, Cuddy and Lucas's relationship becomes more serious.

The team diagnoses a patient who was an acclaimed genius before giving it up to be with his wife. Meanwhile, House starts his plan to break up Cuddy and Lucas by crashing their Thanksgiving dinner.

Wilson treats a friend who has a recoccurence of cancer. Meanwhile, Cuddy places a bid for a loft to move in with Lucas.

The team treats a drug dealer who collapses under stress. The team plays a prank on Foreman to convince him that they are being paid more than him. House pretends he is gay in order to sleep with an attractive female neighbor.

The team diagnosis a woman who has no emotional capacity. The conflict between Foreman and Thirteen creates a dysfunctional workplace. House makes up to an old classmate after ruining his life.

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As this episode follows a day with Cuddy, we watch as she balances work with home, negotiates with insurance companies, reports to the hospital board and deals with personnel issues.

The team treats a woman who is not afraid to share every moment of her life with the world. Wilson discovers House is secretly doing some extracurricular reading.

The team diagnoses a young girl who is hallucinating about black holes.

The hospital is put under lockdown after a baby goes missing. Thirteen and Wilson play truth or dare. Cameron returns and demands Chase sign their divorce papers.

The team treats a medieval knight who has rashes and red eyes. House discovers that Wilson is dating his ex-wife Sam.

House treats a patient who is in an open marriage. Taub hints that he wants an affair. Wilson speaks up after he notices things about Sam that bothers him.

The team treats a man who is hiding his past sexual orientation from his fiance. Since he is reconnecting with his ex, Wilson pays off the staff to take House out.

House attends a therapy session with Nolan and goes over his last week while Wilson kicked him out of the condo.