At the hotel, Boa Vista and Horatio see that Jimmy's tire iron is clean. The tire iron owned by the valet is tested and found positive for blood. The valet admits he was bribed by Jimmy to flatten Ashley's tires.

Tom tells Calleigh he thinks the leg was removed post mortem. He finds an alkaline substance on the woman's foot. They learn the substance is salt and sand from a beach. They discover that the sample has high traces of salt, iodine and plutonium. Calleigh figures that the sample was from Nevada. Horatio orders Calleigh to contact the Las Vegas police. Calleigh contacts Ray Langston from CSI. Ray asks if the victim had a tattoo on her ankle and after confirmation Ray informs them the victim is Samantha Matthews who went missing ten days ago. They see that both of the victims were wannabe models who came from small towns.

Ray arrives at Miami and meets with Horatio. They go to the scene and figure animal scavengers dispersed the body parts.

Tom is introduced to Ray Langston. Tom tells Ray he admires his work. They examine Samantha's body and wonder what kind of blade cut the leg. Ray says he brought several samples to compare. Ray figures the cut was made by a commercial grade cleaver. They figure they are looking for a butcher.

Benton tells the team he has isolated butcher shops in the area, but there are several hundred possibilities. They see that there is one restaurant owner who has a business in both Miami and Las Vegas. Ray and Horatio go to the restaurant owned by Nathan Cole. Ray informs Cole they know he has a signature cutting style in which he uses one stroke to cut. Horatio tells Cole they know he was in Las Vegas when Samantha died. Ray tells Cole he would like to do a hematrace on his cleaver. After the test, Ray tells Horatio he found human blood on the cleaver. The police arrest Cole and take him to the station.

Back at the lab, the police are unable to match the blood on the cleaver to either victim. Ray reports that the cleaver is a match to the blade that was used to cut Samantha's leg. They see that Cole has a cut in his hand and wonder what caused it. Boa Vista obtains a blood sample from Cole. After they test the blood, Ray informs Cole that he has a unique strain of Hepatitis C like the type found on Samantha. They tell him they suspect he got it while he cut Samantha up.