In Philadelphia, police investigations, that seemingly are at a dead end, reopen by the emergence of fresh evidence. Lily Rush is the lead detective investigating these cold cases. Witnesses are questioned and they retell the events of the crime that happened in the distant past. The Cold Case team piece the clues together and finally bring justice to a victim long forgotten.

In 1973, the Warriors football team was on their way to becoming champions, but their dreams came crashing down when their star running back was found murdered.

In 1991, an inspirational teacher was murdered and her killer was never found. Was it the security guard, a student, or someone else?

An old letter reopens an investigation of the death of a housewife in 1964 who was living a secret life of fighting for civil rights.

A woman's memory reopens a case from 1978 involving the death of a teenage roller skating speedster who was found in a ravine.

A murder case is opened and the team investigates after the body of a Marine who went missing in 1951 is found inside an old oil barrel.

A woman's body is found in the back of a car and it leads the team to investigate her work life at a car dealership and a murder case from 1981.

A rocket turned into the police reopens a case from 1969 involving a young boy who was murdered on the same day man walked on the moon.

The team reopens the 1989 murder case of a young aspiring singer who's life was cut short after defecting to the United States from Russia.

The team looks into the unsolved murder of a pinup model killed in 1953 after a fan brings in a one of a kind photograph that reveals details about her death.

The team reopens a 2005 case involving an activist turned politician who had his career cut short after being gunned down in the street.

The body of a flight attendant is discovered and it reopens a case from 1960 while Rush reconnects with a person missing in her life.

The team reopens a 2007 murder case involving a lotto winner who was found dead after spending all of his money when it is discovered that his account was recently accessed.

The team reopens the case of a Philadelphia news anchor who was killed in 1988 when a tape surfaces at the station that shows she was reporting on a scandal.

The team reopens the 1967 murder case of a popular door-to-door salesman after remains are found at the bottom of a drained duck pond.

The team reopens a murder case from 2008 involving a man who was murdered while in the witness protection program after his widow asks them to help find her missing son.

Rush and the crew investigate the death of a 17 year old honor student who was murdered in 1976 after she joined a criminal biker gang.

Jeffries is shot at a convenience store along with the owner of the store and the Cold Case team searches for the perpetrator.

The 2004 murder case of Dr. Julie Ramirez, a psychiatrist who worked with schizophrenics, is reopened and the team investigates. Featuring music by John Lennon.

The team reopens the 1958 murder case of a newlywed real estate developer after new evidence suggests his body was moved after he was killed.

The team investigates the 1999 murder case of a Cuban refugee who escaped to the US to pursue a career in baseball while Vera tries to start his own softball team.

After a murder weapon is discovered, the team looks into the 1963 murder of a pool player who was shot on the same day that JFK was assassinated.

The team re-opens the case of the first ever female cadet in a local military school who was murdered in 2005. This episode features the music of Pearl Jam.

The team continues the investigation into the murder of the female cadet, but the killer tries to prevent them from finding out the truth. Features music by Pearl Jam.

The man that tried to run Rush off the road is released out on bail. The team investigates the murder of a liberated woman who died on a cruise ship in 1966.

The team investigates the death of a skater who ran away from his home in New Jersey.

The team investigates the death of a juvenile delinquent that Valens feels responsible for. Meanwhile, an old flame reignites in Rush's life.

A inspiring church organist turned soul musician is killed in the seventies. The team investigates whether or not his father, girlfriend or studio producer killed him. Meanwhile, Rush meets her half-brother.

The team investigates a woman who they believe was killed because her Airforce plane was sabotaged. Meanwhile, Valens learns his mother is hiding something from him.

The team investigates a horse jockey who was dumped in a horse pit. Meanwhile, Valens digs deeper to figure out what is going on with his mom.

The team reopens a case about a young aspiring female rapper who was found dead in a dumpster. Meanwhile, Rush gets a surprising anniversary gift from Eddie.

Stillman revists a case involving the death of a Chinese boy thought to be related to gang violence. Meanwhile, Eddie gives Rush extravagent presents.

The team investigates the death of a legendary debater at a private school. Meanwhile, Vera gets a second opinion about his health.

The team reopens a case about an Army recruiter thought to have been killed after he robbed a pawn shop. Rush is invited to be part of Paul's family.

The team investigates the death of a detective who was hired to locate the daughter of a widow. Valens is told to back off his mother's case. Rush continues to make Moe's life difficult.

The investigates the death of a graffiti artist in 1982. Curtis confronts Rush about her revenge against Moe. Miller's ex asks for visitation rights.

The team investigate a groundbreaking acrobat who died in 1971. Rush is questioned about the murder of Moe.

The team investigates whether or not a colleague's bride is a black widow.